Dexbrompheniramine and Pseudoephedrine

Pronunciation

(deks brom fen EER a meen & soo doe e FED rin)

U.S. Brand Names

Drixoral® Cold & Allergy [OTC]

Synonyms

Pseudoephedrine and Dexbrompheniramine

Generic Available

Yes

Canadian Brand Names

Drixoral®

Use

Relief of symptoms of upper respiratory mucosal congestion in seasonal and perennial nasal allergies, acute rhinitis, rhinosinusitis and eustachian tube blockage

Pregnancy Risk Factor

B

Dosage

Children >12 years and Adults: Oral: 1 timed release tablet every 12 hours, may require 1 tablet every 8 hours

Administration

Swallow tablet whole; do not crush or chew

Dietary Considerations

May be taken with food or water.

Patient Education

Swallow whole, do not crush or chew

Dental Health: Effects on Dental Treatment

Key adverse event(s) related to dental treatment: Pseudoephedrine: Xerostomia (normal salivary flow resumes upon discontinuation).

Dental Health: Vasoconstrictor/Local Anesthetic Precautions

Use with caution since pseudoephedrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response

Mental Health: Effects on Mental Status

May cause drowsiness, anxiety, and nervousness

Mental Health: Effects on Psychiatric Treatment

Dry mouth is common; this effect may be worsened by concurrent psychotropic use

Dosage Forms

Tablet, sustained action (Drixoral® Cold & Allergy): Dexbrompheniramine maleate 6 mg and pseudoephedrine sulfate 120 mg

International Brand Names

Drixoral® (CA)