Erythromycin and Benzoyl Peroxide
Pronunciation
(er ith roe MYE sin & BEN zoe il per OKS ide)
U.S. Brand Names
Benzamycin®; Benzamycin® Pak
Synonyms
Benzoyl Peroxide and Erythromycin
Generic Available
No
Use
Topical control of acne vulgaris
Pregnancy Risk Factor
C
Lactation
Excretion in breast milk unknown/use caution
Drug Interactions
Erythromycin:
Substrate of CYP2B6 (minor), 3A4 (major);
Inhibits CYP1A2 (weak), 3A4 (moderate)
Also see individual agents.
Pharmacodynamics/Kinetics
See individual agents.
Dosage
Apply twice daily, morning and evening
Patient Education
See individual agents. This product contains benzoyl peroxide which may bleach or stain clothing.
Pregnancy/breast-feeding precautions: Inform prescriber if you are or intend to become pregnant. Consult prescriber if breast-feeding.
Nursing Implications
Apply after skin is washed, rinsed with warm water, and gently patted dry; contains benzoyl peroxide which may bleach or stain clothing
Dental Health: Effects on Dental Treatment
No significant effects or complications reported
Dental Health: Vasoconstrictor/Local Anesthetic Precautions
No information available to require special precautions
Mental Health: Effects on Mental Status
None reported
Mental Health: Effects on Psychiatric Treatment
None reported
Dosage Forms
Gel, topical:
Benzamycin®: Erythromycin 30 mg and benzoyl peroxide 50 mg per g (47 g)
Benzamycin® Pak: Erythromycin 30 mg and benzoyl peroxide 50 mg per 0.8 g packet (60s) [supplied with diluent containing alcohol]